<div class="bodyItems-wrapper">   <p class="yf-7hmkaz">Dec 19 (Reuters) - BioMarin Pharmaceutical (<a data-i13n="cpos:1;pos:1" href="https://finance.yahoo.com/quote/BMRN/" data-ylk="slk:BMRN;cpos:1;pos:1;elm:context_link;itc:0;sec:content-canvas" class="link ">BMRN</a>) said on Friday it would acquire Amicus Therapeutics (<a data-i13n="cpos:2;pos:1" href="https://finance.yahoo.com/quote/FOLD/" data-ylk="slk:FOLD;cpos:2;pos:1;elm:context_link;itc:0;sec:content-canvas" class="link ">FOLD</a>) for about $4.8 billion, expanding ​its presence in rare metabolic diseases.</p>   <p class="yf-7hmkaz">The drugmaker will ‌pay $14.50 per share for Amicus, a premium of 33.1% to the stock's last ‌close. Shares of Amicus surged 30%, while BioMarin rose nearly 5% in premarket trading.</p>   <p class="yf-7hmkaz">The deal strengthens BioMarin's portfolio with Amicus' approved genetic disorder treatments including Galafold, an oral drug for ⁠Fabry disease, which ‌is caused by a faulty gene that leads to a buildup of fatty substances in cells.</p>   <p class="yf-7hmkaz">Amicus ‍also markets a combination therapy Pombiliti and Opfolda for Pompe disease, a genetic condition in which a complex sugar called glycogen builds ​up in the body's cells.</p>   <p class="yf-7hmkaz">Amicus also has U.S. rights ‌to DMX-200, a potential treatment of a type of kidney disease known as focal segmental glomerulosclerosis.</p>   <p class="yf-7hmkaz">BioMarin intends to finance the deal through a combination of cash on hand and about $3.7 billion of non-convertible debt financing.</p>   <p class="yf-7hmkaz">The company's total cash and ⁠investments at the end of ​September 30 were about $2 billion.</p>   <p class="yf-7hmkaz">The acquisition, ​which is expected to close in the second quarter of 2026, will add revenue immediately after the ‍transaction closes, ⁠BioMarin said.</p>   <section class="card variant-default tw-mb-6 yf-1fx3q76 elevation3"><form method="POST" class="yf-1fx3q76"><div class="fin-newsletter-img-wrapper yf-1fx3q76"> <img class="tw-bg-opacity-25 tw-h-full tw-w-full tw-object-cover yf-1ev0m0b" alt="Yahoo Finance Daily Movers" src="https://s.yimg.com/cv/apiv2/finance/newsletter/yfdm_v1.jpg" fetchpriority="auto" loading="lazy"></div> <div class="header-container yf-1fx3q76"><label for="dailyMovers-input"><header class="x-small tw-mb-0 mb-0 yf-1kayatz font-condensed"><h3 class="header  yf-1kayatz">   <span style="--base-variant: var(--font-label-md-emphasis); --tablet-variant: var(--font-label-md-emphasis); --desktop-variant: var(--font-label-md-emphasis); text-decoration: none; font-style: normal; text-transform: none; text-align: inherit;" class="text    yf-1xj3fin">Sign up for Yahoo Finance Daily Movers </span></h3> </header> </label> <span class="newsletter-info yf-1qiord2"><span class="container tw-flex tw-items-center tw-py-4 -tw-my-4 yf-1ouvapf"><div aria-hidden="true" class="icon fin-icon inherit-icn sz-x-large  yf-sv6wwp"><svg xmlns="http://www.w3.org/2000/svg" viewbox="0 0 24 24"><path d="M11 7h2v2h-2zm0 4h2v6h-2zm1-9C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.41 0-8-3.59-8-8s3.59-8 8-8 8 3.59 8 8-3.59 8-8 8"></path></svg> </div> <div class="tooltip al-top tw-z-10  yf-1ouvapf" role="tooltip"><div class="arrow yf-1ouvapf"></div>        <span style="--base-variant: var(--font-label-sm-reg); --tablet-variant: var(--font-label-sm-reg); --desktop-variant: var(--font-label-sm-reg); color: var(--color-text-icon-secondary, inherit); text-decoration: none; font-style: normal; text-transform: none; text-align: inherit;" class="text    yf-1xj3fin" slot="content">By subscribing, you are agreeing to Yahoo's 
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Dec 19 () - BioMarin Pharmaceutical said on Friday it would acquire Amicus Therapeutics for about $4.8 billion, expanding ​its presence in rare metabolic diseases.

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